Regenerative Medicine at Greenwich MD: physician-led PRP, PDGF, and PDRN protocols that work with the body’s own biology to stimulate tissue repair, collagen production, and cellular renewal across the face, scalp, neck, and beyond. Related: Aesthetic Medicine at Greenwich MD →
Medically reviewed by Susana Querido, MD – Triple Board-Certified in Family Medicine, Aesthetic Medicine, and Anti-Aging & Regenerative Medicine. Medical Director, Greenwich MD.
Regenerative medicine treatments use the body’s own biological signals, or closely biology-mimicking compounds, to repair tissue, stimulate collagen, and renew cells from the inside out. Rather than covering a concern with a filler or masking it with a surgical procedure, regenerative protocols activate the mechanisms the body already uses to heal itself. At Greenwich MD, this means three distinct but complementary approaches: platelet-rich plasma and platelet-rich fibrin (PRP/PRF), platelet-derived growth factor therapy (PDGF), and polynucleotide therapy (PDRN). Each works through a different biological pathway, and each can be matched to a patient’s specific goals, anatomy, and tissue condition.
The field sits at the intersection of aesthetic medicine and anti-aging science. It’s not about looking artificially different. It’s about restoring tissue quality, density, and function in ways that develop gradually and hold over time. For patients who want results that don’t announce themselves as “treatments,” regenerative medicine offers a compelling alternative to approaches that simply add volume or relax muscle.
Each of the three regenerative modalities at Greenwich MD targets a specific layer of the repair cascade. PRP and PRF concentrate the patient’s own platelets, which release growth factors that signal fibroblasts and stem cells to begin producing collagen and new tissue. PDGF therapy delivers a concentrated, standardized dose of platelet-derived growth factors to accelerate the same repair and remodeling signals with greater precision. PDRN therapy uses purified polynucleotide fragments (short chains of DNA) that activate adenosine A2A receptors in the skin, directly stimulating fibroblast proliferation, reducing inflammation, and supporting the formation of new extracellular matrix. Together, these approaches give Dr. Querido the ability to address different depths and different biological deficits within a single, coordinated treatment plan.
Triple Board Certification: Dr. Querido holds board certifications in Family Medicine, Aesthetic Medicine, and Anti-Aging and Regenerative Medicine. That last certification isn’t incidental to this page. It means her training in regenerative medicine is formal, examined, and continuously updated, which directly shapes how protocols are selected, sequenced, and monitored at Greenwich MD.
Physician Oversight: Dr. Querido directly oversees every regenerative medicine program and personally performs every treatment based on the patient’s plan. No regenerative protocol at this clinic is delegated to a nurse practitioner or physician assistant. From the initial consultation through the final maintenance session, the same physician assesses, injects, and adjusts. That continuity matters clinically, because tissue response to regenerative treatments is cumulative and nuanced, and subtle changes between sessions inform what happens next.
Integrative Approach: Dr. Querido doesn’t select a single modality and apply it uniformly. She evaluates each patient’s goals, existing tissue quality, age-related changes, and response to prior treatments, then builds a protocol that may combine PRP/PRF, PDGF, or PDRN with complementary procedures. This individualized structure is what separates a regenerative medicine practice from a clinic that simply offers “PRP as a service.” Learn more about Dr. Querido’s background →
Regenerative treatments aren’t one-size-fits-all by location any more than they are by modality. The face, scalp, neck, décolletage, and hands each present different tissue depths, cell turnover rates, and collagen architectures. Dr. Querido tailors both the choice of regenerative agent and the delivery method to the specific anatomy being treated. And in most cases, regenerative protocols are most effective when combined with a procedure that creates controlled microchannels or thermal stimulation, allowing the biologic agent to reach the target depth and activate the repair cascade more efficiently.
Microneedling creates thousands of micro-injuries that trigger the skin’s natural wound-healing response while simultaneously opening channels through which regenerative agents such as PRP or PDRN can be delivered more deeply. This pairing is particularly effective for skin texture, fine lines, and early collagen loss. Learn about microneedling at Greenwich MD →
Radiofrequency microneedling adds a thermal dimension to the mechanical stimulation of standard microneedling. The heat signal triggers a secondary collagen remodeling cascade in the deeper dermis, and applying a regenerative agent in conjunction amplifies the cellular response. This combination is well-suited for patients dealing with skin laxity, textural irregularity, or more pronounced collagen depletion. Explore RF microneedling options →
Skinbooster treatments deliver hydrating agents into the dermis to improve skin quality at the structural level. When combined with PDRN or PDGF therapy, the two protocols address different but complementary deficits: one restores hydration and surface quality, the other drives fibroblast activity and deeper tissue renewal. Read about skinbooster protocols →
PRP/PRF is among the most clinically studied non-surgical options for hair thinning and early hair loss. Delivered to the scalp, it delivers concentrated growth factors directly to the follicular unit, supporting the anagen (growth) phase and improving follicular density over a series of sessions. Learn about PRP for hair loss →
Regenerative medicine treatments work cumulatively. A single session will produce some effect, but the tissue remodeling response deepens meaningfully across a structured series. Greenwich MD’s standard initial protocol runs three sessions spaced 30 to 45 days apart, which allows each round of biological stimulation to complete its primary repair cycle before the next session layers additional signal on top. After the initial series, annual maintenance sustains the gains. The table below describes the general structure.
| Phase | Sessions | Notes |
|---|---|---|
| Initial series | 3 sessions, 30 to 45 days apart | Each session builds on the previous one; Dr. Querido assesses tissue response between visits and adjusts the protocol if needed |
| Maintenance | Annual (typically one session per year after the initial series) | Sustains collagen remodeling and tissue quality; specific interval may vary based on individual response and treatment goals |
Regenerative medicine treatments are well-suited for patients who want results that improve tissue quality rather than simply change how a feature looks. They’re particularly appropriate for patients who prefer physician-administered protocols, want minimal downtime, and are thinking in terms of long-term skin health rather than a single-event result. Good candidates generally include:
Regenerative medicine treatments aren’t appropriate for everyone. Patients with active infections at the treatment site, certain autoimmune conditions, a history of blood disorders, or current use of anticoagulant medications may not be suitable candidates. Pregnancy is also a contraindication for most regenerative protocols. Dr. Querido reviews each patient’s full medical history at consultation to confirm suitability before any treatment plan is finalized.
Regenerative medicine treatments at Greenwich MD are available to patients in Stamford, Greenwich, Darien, New Canaan, Westport, Norwalk, and the surrounding area. To find out which combination of PRP/PRF, PDGF therapy, or PDRN therapy fits your goals, schedule a consultation with Dr. Querido at 1351 Washington Boulevard, Suite 803, Stamford, CT 06902. She’ll review your anatomy, your objectives, and your health history before recommending a protocol, so you leave with a clear, honest plan rather than a generic treatment menu.
Our Stamford clinic is conveniently located for patients throughout Fairfield County:
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